Cost-Effectiveness Analysis
Overview
Cost-effectiveness is a key factor in the prioritization of health products. This document outlines how cost-effectiveness data is captured and displayed in the ALIGN Global Hub.
Methodology
1. Data Collection
Cost-effectiveness data is gathered from peer-reviewed literature, health technology assessment (HTA) reports, and global health organization publications.
2. Standardized Metrics
Where possible, the Hub uses standardized metrics to allow for cross-product comparison:
- Cost per DALY Averted: The cost required to avoid one Disability-Adjusted Life Year.
- Cost per Case Averted: The cost required to prevent one case of the target disease.
3. Data Presentation
In the Global Hub, cost-effectiveness is typically represented as:
- Comparative Benchmarks: Showing how a product’s cost-effectiveness compares to existing standards of care.
- Categorical Ratings: High, Medium, or Low cost-effectiveness based on established thresholds (e.g., WHO-CHOICE thresholds).
Current Limitations
- Data Fragmentation: Cost-effectiveness data is often not available for products in early development.
- Context Specificity: Cost-effectiveness can vary significantly across different geographic and health system contexts.
Future Enhancements
ALIGN is working to integrate more dynamic cost-effectiveness modeling tools into the Hub, allowing users to estimate impact based on country-specific cost and epidemiological parameters.
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